Here is a bug I came across that seems to be Win2000 related:
I have a picture database. I can display one picture and then close it either by double clicking in the results window or clicking on it in the insert/update table window.
As soon as I click on another picture, SQLyog will crash
I can choose any picture and display it for the first time, any picture that is chosen second will crash SQLyog.
This behaviour only happens with the Windows 2000 computers I have – it doesn't happen with a Windows Me computer.