Most of the time, the pre-configured keyboard shortcuts are fine. However, for specific reasons, it would be convenient to be able to 'disable' shortcuts for some drastic database operations.
It can be pretty dangerous to accidentally press 'del' on your keyboard when you think you are editting notepad on your right-hand screen, while the focus is on sqlyog on your left-hand screen.
Also, the shortcut for the truncate-table function (shift+del) is almost the same as the shortcut for deleting a table (del). I always double check if the confirm-dialog really mentions 'truncate', there can always be a moment when you don't combine the shift+del well.
It is a request for a pretty specific reasons, but we have found ourself removing objects from our database on accident.